Best Estrogen Blocker for Prohormone Cycles: Estrogenex Depot or 2nd Generation?

If you're looking for the best on-cycle support supplement or an effective estrogen blocker, chances are you've come across Estrogenex Depot and Estrogenex 2nd Generation. While both are popular products among those running prohormone cycles, many useres are unsure about the key differences between the two. Let's breakdown exactly what sets these two formulas apart and help you decide which one is better suited to your specific goals. 

Estrogenex Depot: For Agressive Estrogen Blocking

If your primary concern is aggressive estrogen suppression, Estrogenex Depot is the stronger of the two options. Here's why:

• Multiple Aromatase Inhibitors: This formula includes a blend of powerful aromatase inhibitors designed to significantly reduce estrogen levels. 
• Includes Epiandrosterone: Known for its muscle-hardening and anti-estrogen properties. 
• Best For:
  • Those highly sensitive to estrogen spikes
  • Users on stronger prohormones such as Sustanon 250 or heavy 4-andro stacks
  • Anyone wanting to prioritize estrogen suppression during a cycle

If you're running a heavy cycle and want to keep estrogen under control, Estrogenex Depot is the go-to. 

Estrogenex 2nd Generation: For Balanced Support and Natural Test Boosting

On the other hand, Estrogenex 2nd Generation takes a more balanced approach. While it's less aggressive on estrogen blocking, it shines in its natural tesotsterone boosting capabilities:

• Key Ingredients:
  • Eurycoma Longifolia: Supports natural testosterone production
  • Quercetin: May assist with hormone regulation
  • Muira Puama: Traditionally used to support male vitality
• Best For:
  • Those who aren't running prohormones
  • Users who perfer a mild estrogen blocker during lighter cycles
  • Anyone wanting a natural testosterone support supplement

If you're someone who likes to include an estrogen blocker in every cycle, even when not stricktly necessary, this is a well rounded choice.

Final Thoughts: Choose Based on Your Goal

To recap: