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Metabolic Nutrition Synedrex 45 Caps

Metabolic Nutrition Synedrex 45 Caps

Sku: 764779224592
Regular Price: $54.95 (-$5.00)
Special Price $49.95



Metabolic Nutrition Synedrex 45 Caps


BEING REFORMULATED: The new formula will not be released until mid 2017. If you are looking for a replacement, Hi Tech has released Synadrene, which is the exact formula as the original Synedrex with 1,3 DMAA. Synadrene is available now here.


What is Synedrex?

Metabolic Nutrition Synedrex is a high quality performance fat burner that contains potent thermogenic ingredients to get you shredded. Synedrex contains the world's first 4 step metabolic accelerator. SYNEDREX works by addressing the 4 problem areas which can slow your metabolic rate. SyneDrex is a research-designed gel-cap that stimulates metabolic receptors to burn calories faster. SyneDrex begins to work instantly to increase your metabolic rate. Since metabolism varies from person to person, fat loss results will vary.


  • Speeds Up Your Metabolism
  • Burn More Body Fat
  • Control Appetite
  • Quick, Extended Energy – No Crash!


  • Increases your caloric burn each and every day
  • Stimulates your Energy Levels
  • Controls carbohydrates for maintaining a healthy blood sugar level to control sugar cravings
  • Controls your Hunger so that you spend more time living life than looking for something to eat


Due to the strength of Synedrex please assess your tolerance by initially taking only 1 capsule upon awakening for the first 3 days. After assessment, if effects last longer than 15 hours, consider alternating dosage to every other day. With caution, you may increase up to 2 capsules in the A.M. Do Not take more than 2 capsules daily or 12 hours prior to desired bedtime. Only Phenolox, Thyrene, and Hydravax may be combined with Synedrex for a more customized weight loss solution. Do Not combine with other non approved supplements or medications. Do Not use Synedrex longer than 60 days continuously.


Servings Per Bottle: 45
Serving Size: 1 Capsule

Vitamin B3 (as Niacin): 20mg
Vitamin B6 (as Pyridoxine HCL): 4.25mg
Vitamin B12 (as Cyanocobalamin): 100mcg
Chromium: 175mcg

Synedrex Formulated Weight Loss Solution Blend: 920mg
Methylxanthin: *
Methylpentane Citrate: *
Sulbutiamine: *
Sandalwood Extract: *
Yohimbine Extract: *
Alpha Lipoic Acid: *
Poly-liodo-Thyonine: *

Other Ingredients: DiPotassium Phosphate, MCMC, Silicone Dioxide, Magnesium Stearate, Titanium Dioxide, FD & C Blue 1, Red 40, Ti02, Gelatin

Note: This formula no longer has 1,3 DMAA in it.

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  • From Carrie at 9/10/2015 5:15 PM
    • What happens if I use it for longer then 60 days?
    • Some people do use Synedrex for longer, but it's best to give your body a break from stimulants after that long of use. You could switch to a non-stimulant fat loss product liek Thyrene or Hydravax...and then go back to this again 4 weeks or so later.
  • From dave at 9/20/2015 7:09 PM
    • could there be any bad side effects ....if I take Synedrex in the morning and Tylenol or Ibuprofen at evening/night ??
    • There shouldn't be any negative side effects, as doing that is common among bodybuilders and athletes. But if you do have concerns, we would recommend speaking with your doctor.
  • From Ben at 9/25/2015 9:01 AM
    • If I take one in the morning before work, am I able to still take a pre workout before the gym that day? Does mixing this with pre/post workout powders have any side effects/problems?
    • Yes you definitely can. Just make sure to get at least 4-6 hours between taking one capsule of Synedrex and your pre-workout supplement. You can also mix this with a pre-workout as long as it is non-stimulant. We would not recommend taking a stimulant fat burner and a stimulant pre-workout at the same time together.
  • From Caroline at 1/14/2016 4:53 PM
    • Can this make me "pop hot" on a drug test? Or is there any ingredient not listed? I know the old formula had that 1 3 dimethylamylamine in it and I was not allowed to take it.
    • No, there shouldn't be anything in here that would make you fail a drug test. Now it really depends on what they are testing for though. This formula does have Amp Citrate, but not 1,3 DMAA.
  • From Chase at 1/28/2016 5:35 PM
    • Is it okay if I take this while taking l-carnitine and pre workout? I do not use pre workout daily but I use it frequently.
    • You can stack it with the L-Carnitine no problem. As far as the pre-workout, you have a couple options. Stack it with a non-stimulant pre-workout or don't take it within 4-6 hours of your pre-workout supplement.
  • From Andy at 3/6/2016 2:01 PM
    • What happens if you drink alcohol, caffeine or sugar while taking this?
    • It is not recommended to take in alcohol or caffeine from other sources at the same time as taking this. Now if you take this in the morning, and drink at night or take in other caffeine at night, that is no problem.
  • From Andy at 3/9/2016 10:47 AM
    • Good morning. I have a question with regards to the amount of pills taken in a day. I noticed it says to take one pill for three days, and after that you can take two. What I'm a bit confused on is if after the third day you take two at a time, or you take one in the morning, or if you take one in the morning and then another one four or five hours later?
    • In the beginning you are just accessing your tolerance. Once your tolerance is accessed, you can do it two ways. Taking both at the same time, or if that is too strong, take one upon waking and another 4-6 hours later. Just don't take in the afternoon or evening, as it can keep you up at night due to the strength.
  • From Paola at 4/11/2016 4:35 PM
    • What is the expiration date of the product? I'm thinking about buying like 4 at the same time...
    • Our current stock (as of 04/12/2016) of Synedrex expires 07/2018, so you have over two years left on each bottle.
  • From dave at 5/8/2016 7:13 PM
    • I'm taking Pantoprazole for g.e.r.d. would it be safe to take synedrex ? still....I went through a whole bottle of one already of synedrex...but I still have one unopened bottle it expires 2018..since they barely discover I have gastro esophageal reflux diseas..
    • You would need to speak to your doctor. Anyone having any sort of medical condition or taking a prescription medication should always speak to their doctor before taking any type of dietary supplement.
  • From M at 6/7/2016 4:24 PM
    • Is this the original formula with DMAA or the newly formulated product?
    • Synedrex hasn't had 1,3 DMAA in it for about 2-3 years. It was reformulated about 2 years ago with AMP Citrate. Now the newest version doesn't have AMP Citrate, but all our bottles still have the formula with AMP Citrate, which is the one you want. If you are looking for a product with 1,3 DMAA we would recommend HydroxyElite Pro or Lipodrene, both which you can find at MySupplementStore.com. Hope this helps!
  • From Salina at 7/24/2016 10:28 PM
    • Does the bottle have meridextrine in it?
      Ti02 in it?
    • This is what Metabolic Nutrition told us:

      "Meridextrin is a fine-particle core product that is a mechanically stable granulate consisting of spherical particles with an average size of about 30 micrometers (or 30 millionths of a meter). The highly porous granules of pure silicon dioxide are eminently suitable as carrier substances for active ingredients that must be incorporated into powder formulations in precise measurements. Meridextrin also prevents interaction between ingredients to preserve the chemical structure of each active so that it maintains it intended functionality…and by this same nature it can exhibit a time-release functionality as well."

Customer Reviews

5 Stars (31)
4 Stars (5)
3 Stars (1)
2 Stars (2)
1 Stars (0)
Oct 21, 2016
Yes it worked Great. I've taken it before and love the way it makes me feel.
*DISCLAIMER. Individual results may vary.
Sep 13, 2016
Finally a product that helped me lose extra weight. This along with a diet will really help!
*DISCLAIMER. Individual results may vary.
Sep 07, 2016
Awesome fat burner. Feel great on it. I just stocked up as I heard this is going to be discontinued.
*DISCLAIMER. Individual results may vary.
Sep 02, 2016
Love this fat burner. Always works for me.
*DISCLAIMER. Individual results may vary.
Jul 20, 2016
By far the best fat burner out there..!!!!!
*DISCLAIMER. Individual results may vary.
Jun 28, 2016
awesome. works amazing. was given some from a friend before. have lost 40lb!!! i have no appetite during the day. probably cause they make me feel like im in a constant state of mild nausea. but ill take it! seriously. never have i ever bought a diet pill that actually seemed to "work". theres a ton of other stuff in it though, and it definitely gives me a little bit of the shakes in the morning on an empty stomach but if i eat something small it goes away pretty quick. im on my second bottle now. ive only ever taken one a day. 2 would be crazy.
*DISCLAIMER. Individual results may vary.
Jun 22, 2016
By far the best supplement in this category!
*DISCLAIMER. Individual results may vary.
Jun 02, 2016
In my opinion, this is awesome. Helps boost energy. Keeps your mind off food throughout the day.
*DISCLAIMER. Individual results may vary.
May 11, 2016
Make sure you eat something before taking the pill. It does help curb your appetite. Hopefully it helps me lose some unwanted pounds.
*DISCLAIMER. Individual results may vary.
Mar 29, 2016
Seems would be good for ADHD/ADD people. This drug decreases my energy, appetite, and i didnt see any difference in my muscle tone vs testosterone supplements. I was excited to use this product, synerdrex, that was recommended to me. But so far have been disappointed. I have been using it daily for almost a week with no effects (besides some occasional gas and stomach cramps and loss of appetite ). I believe since I have a history of ADHD/ ADD That this product has AN OPPOSITE EFFECT. Usually stimulants with this population help slow down the individual and help them concentrate..and that's what I feel is happening to me...smh I do not get thirsty, excessive energy, or any other benefits out of this. I really was hoping for more energy while I worked out... I'm going to complete my bottle and then reflect . Hope this helps.
*DISCLAIMER. Individual results may vary.
Mar 25, 2016
Great.would buy again...
*DISCLAIMER. Individual results may vary.
Feb 27, 2016
yes it worked good!
*DISCLAIMER. Individual results may vary.
Feb 18, 2016
I use one before training with a protein shake or oatmeal. keeps me going and makes me sweat. I recommend drinking plenty of water as it makes you thirsty. I drink 4 -5 16.9oz bottles during workout.
*DISCLAIMER. Individual results may vary.
Feb 04, 2016
Definitely works as described - fantastic appetite suppressor
*DISCLAIMER. Individual results may vary.
Jan 20, 2016
Way better than I ever expected!
*DISCLAIMER. Individual results may vary.
Jan 13, 2016
I'm sure this is effective for others but it's definitely not for me. Today was the first day I took Metabolic Nutrition Synedrex. It was referred to me by the people at Nutrition Depot. They did warn me that if you do not do well on stimulants, to stay away from this product and go with an alternative. Since I've taken OxyElite Pro before and with pretty good results, I thought I'd be able to handle this. Well I've since realized, I can't. I'm sure this is effective for others and I'm almost positive that it works by reducing your appetite and help with weight loss but in this case, the side effects outweigh the pros. I took my first pill upon waking like the bottle suggests. It was 7:15am. By 7:30 I started to feel a bit "weird". I have an hour commute to work each morning and by 8:00am I felt it in full force. I had nausea, dry-heaving, the inability to control my body temperature, cold sweats, perspiration and tingly hands and feet! It kinda makes me feel like I'm on X to be honest with you. It's a horrible feeling; no wonder people don't eat with this. You feel too sick and too nauseated to put anything near your move. When I got to work around 8:30 am and thinking it would help - I ate a whole wheat bagel and cream cheese and drank a TON of water. By 11:30 am I was still feeling it's affects. I read that it can take anywhere between 15 hours and several days for it to pass through your system. The rep at Nutrition Depot said to give it at least 3 days but I don't think I can handle this again. I refuse to put myself through this so during lunch, I am returning this bottle. I have been on a diet an exercise program the last several months and cannot kick the last 15-20 pounds from after having a baby. I was hoping that this would help me supplement my regime and kick my ass into high gear and help me lose these last few pounds. This product however; is not for me and I DO NOT RECOMMEND this to anyone that is either sensitive to stims or have never taken a fat burner. Although I was able to handle OxyElite well, this one didn't go over too well with me. I will just have to continue looking for something that works for me instead of trying to conform to something that doesn't. I hope this review helps others decide if this is something that they should try -- or in my case, NOT.
*DISCLAIMER. Individual results may vary.
Oct 13, 2015
I've lost 55 lbs in just over 18 months. Great product!!!!
*DISCLAIMER. Individual results may vary.
May 23, 2015
I started taking synedrex when I got home from vacation last week (didn't know what type of side affects it would have on me and didn't want to risk it ruining my vacation) the first day I started I got incredibly hot and enough energy to last a week, had a little trouble sleeping but by day 2 that pretty much went away. I do need to eat before i take these in the morning, they suppress your appetite so much that you forget that you have not eaten all day until you lay down at night. They do give you a bit of cotton mouth which on my eyes is a good thing because it is making you drink alot of water! Today is day 7 of Taking these pills and I am down 10lbs! As I do not know the long term effect of these pills I can not give a full review but I will be back to let you know! Thanks so much for the awesome product!
*DISCLAIMER. Individual results may vary.
May 12, 2015
W0W ! This synedrex stuff is powerful . I take one pill 1st am while I get dressed for work and immediately it kicks in with the energy . I feel the energy thru the whole day ( I use to fall asleep @ work) I do not feel hungry but force myself to eat so I won't get sick . I made a big mistake one day and took one pill 1st am then took a second pill around 12:30 without eating and it freaked me out bad . it was way to much for me I could not even drive . please be careful and make sure you eat and drink water. the only strange side effect I get is chills . other than that this pill does wonders
*DISCLAIMER. Individual results may vary.
Apr 30, 2015
Very glad this Synedrex product is back after being off the market for part of last year (2014). If you are looking for appetite control/suppressant, look no further. You should take this with some food and be prepared to not get hungry for a long while and also to drink a lot of water as this makes me very thirsty. I've been about to lose over 50 lbs as i do not eat as much and give much needed energy to exercise after a long tiring day.
*DISCLAIMER. Individual results may vary.
Apr 12, 2015
I needed more enquiry and an appetite suppressant. This product is amazing with both of these issues! I will order this product again!
*DISCLAIMER. Individual results may vary.
Mar 15, 2015
This was my very first time using Synedrex. I followed the directions as stated, but I took the one pill during lunch...a big NO NO. I did not go to sleep and crashed around 4AM. The pill definitelyu gave me the energy I was looking for, but I am not sure how long it will take for my body to adjust to it. The energy was unreal!
*DISCLAIMER. Individual results may vary.
Feb 19, 2015
Synedrex is definitely my magic pill! It gives me the energy, endurance and focus that I need. It leans me out by burning all body fat. This pill in combination with a healthy meal plan and good workout routine will work for just about anybody!
*DISCLAIMER. Individual results may vary.
Dec 14, 2014
I have used several of the fat burners available here and Syendrex is by far the best and most potent.
*DISCLAIMER. Individual results may vary.
Nov 20, 2014
My husband and I take synedrex regularly with breaks in between. Out of all of the weight loss supplements we have tried synedrex works the best. Synedrex gives you the focus and energy you need to get through the day and get through your workouts without the crash. Synedrex curbs your appetite and even when we take a break we don't notice intense weight gain like when you take other supplements. Synedrex works great with our body building routine. Highly recommended!

You must always follow a sensible diet!
*DISCLAIMER. Individual results may vary.
Sep 22, 2014
Just 1 pill a day and you will get the result you want. But drink a lot of fluids.
*DISCLAIMER. Individual results may vary.
Jul 09, 2014
Synedrex delivers results!!! No gimmicks if you tried all other diet supplements and felt disappointed you will not regret using Synedrex!! 1 pill a day its all it takes. Happy with results!!
*DISCLAIMER. Individual results may vary.
Jul 09, 2014
Awesome. Love it. So glad it's back!
*DISCLAIMER. Individual results may vary.
Jun 18, 2014
Lisa S.
I would def recommend Synedrex but only to those with good health. I would also only recommend one per day and not drink coffee or anything with caffeine in it as it will only enhance side effects. I love not feeling like I need to stuff my face with something. In fact food is the least on my mind. DO DRINK LOTS OF WATER, maybe a glass per hour. Also, if you feel no hunger even the next morning then skip a day taking the pill. It's only day three and i've lost 3lbs already. The first day is the hardest because your body is not use to it. I don't like coffee so I don't drink caffeine at all so when I first took this pill the side effects were a little strong. Then after the first day I felt better just slight pressure on my chest. Good luck and be safe and smart!
*DISCLAIMER. Individual results may vary.
May 13, 2014
This product is great but you need to be careful. When you first start taking it your body heats up, heart starts to race and your skin looks sunburnt from the active ingredients. Once you take it for a couple of days your body gets used to it and you can go on with your workout as intended to. The label says that once you get used to the effects you can take 2 pills upon waking up. I DO NOT RECOMMEND THIS! These pills are too powerful and you'll actuslly feel like shit for the majority of your day. I know this from experience as I had to cut my workout short the other day which NEVER happens. After going back to the one tablet in the morning I felt fine again the next few days and will never again take two pills in the morning. This is s great product that definitely helps you in the gym but you need to be cautious of how your body will react to the ingredients. If the one pill is too much for you in the beginning you can try opening the capsule and taking half of what is inside.

Hope telling you about my experiences with this product helps others who are looking to make a purchase
*DISCLAIMER. Individual results may vary.
Jan 22, 2014
this is the best!!
*DISCLAIMER. Individual results may vary.
Jan 13, 2014
I love this Synedrex stuff. It really has curbed my appetite. In 6 weeks ive lost over 16 lbs im more motivated and can work out longer.
*DISCLAIMER. Individual results may vary.
Jan 01, 2014
Bought these up before the sold out. Myself and many people I know have had great losses with this product.
*DISCLAIMER. Individual results may vary.
Dec 24, 2013
Synedrex is awesome! As long as I eat enough when I take it! If not I get pretty bad nausea. I also love the appetite suppressant. Down 4 pounds in 1 week so far.
*DISCLAIMER. Individual results may vary.
Dec 18, 2013
Big M
Took as a preworkout, gave more energy than any fat burner I have tried before. Even topped my favorite, SuperHD. I took it in the morning and didn't get any sleep the next night though. But Id definitely take it again
*DISCLAIMER. Individual results may vary.
Dec 09, 2013
Works effectively send me coupons so I can order more thanks guys have a Merry Christmas and a Happy New Year!!!!!!!
*DISCLAIMER. Individual results may vary.
Oct 26, 2013
I loved this product!!! It was a little pricey but worth every penny.
*DISCLAIMER. Individual results may vary.
Oct 21, 2013
This supplement is great as a meal suppressant...I didn't think about food at all which was great since I was dieting for a show and starving all the time. It also gave me really good positive energy with no crash.

I've had friends that have taken this product but they got different results...most of them experienced a severe increase in heart rate, but I'm not that sensitive to caffeine.

Definitely start out with one pill to assess your tolerance level.
*DISCLAIMER. Individual results may vary.
Aug 27, 2013
I'm excited about this product which was recomended by a body building friend. It gives me the energy I need to get through my daily work outs. I have noticed a significant loss of body fat and huge energy boost! I definitely recommend this product
*DISCLAIMER. Individual results may vary.

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