Top 5 Low Calorie Protein Powders

Looking for a low-calorie protein powder that helps you hit your macros without blowing your calorie count? Whether you're cutting, meal prepping, or simply want to optimize your shakes, we’ve rounded up 5 of the best high-protein, low-calorie protein powders you can buy in 2025. All of these range from just 80 to 130 calories per scoop, with 20–28g of protein. Perfect for anyone who’s trying to lean out, prep for summer, or stay on track while enjoying great flavors.

Nutrabio Clear Whey Isolate - Only 80 Calories

• 80 Calories and 20g of protein
• Super clean formula
• Refreshing, juice-like texture
• Best-tasting clear whey 

This one's the lowest calorie protein powder we carry. If you're looking for something light and refreshing—especially for summer or post cardio—this is your go to. Think Isopure throwback but cleaner and smoother. 

Rule 1 Clear Isolate - Refreshing & Light

• 90 Calories and 20g of protein
• Tastes like flavored water with aminos
• Great for HIIT and cardio sessions
• Another excellent clear protein isolate option

Like Nutrabio, Rule 1's Clear Protein is made for warm weather or anyone who doesn't want a creamy shake. It is refreshing and mixes easily without clumping.

Farm Fed Whey Protein - Tastes Great

• 100 calories and 25g of protein
• Includes digestive enzymes for better absorption
• Marshmallow Milk is a fan favorite

This one hits the sweet spot of flavor and function. It's low in calories but still filling—thanks to added enzymes. 

ISO PWDR by Metabolic Nutrition—Flavor Frist & Lean Build

• 104 Calories and 26g of protein
• Standout flavors like Birthday Cake and Muscle LEan 
• Great Texture and smooth mixability
• Solid option for everyday use

If you want lean protein with dessert-like flavors, ISO PWDR delivers. Great for daily shakes or pairing with a carb-source post-workout. 

Isomorph 28 — Highest Protein, Still Low Calorie

• 130 calories and 28g of protein
• Ultra-pure whey isolate
• Unique flavors like Neapolitan, Honey Granola, and two types of chocolate/vanilla 
• Ideal for anyone looking to maximize protein per calorie

Yes, it's the highest in calories on this list—but you're also getting more protein per scoop than most. If flavor variety and protein density matter, Isomorph 28 is a top-tier pick. 

Why Go Low-Calorie with Your Protein?

• Perfect for cutting phaases for summer prep
• Keeps daily calorie intake lower without sacrificing macros
• Great for those drinking 2-3 shakes per day 
• Helps save 100+ calories a day depending on use
• Easy to work into recipes, smoothies, and on-the-go meals 

Final Thoughts

Choosing a low-calorie protein powder is a simple, effective way to stay lean, support your fitness goals, and get your daily protein in without extra macros. Click here, to watch our YouTube videos where we continue to talk about the Top 5 Low Calorie Protein Powders. If you have any questions or need help choosing the right one, feel free to contact us. We are always here to help.